The Autonomous Community of the Region of Murcia (Spanish: Comunidad Autónoma de la Región de Murcia) is one of Spain's seventeen autonomous communities, located in the southeast of the country, between Andalucía and Valencian Community, on the Mediterranean coast.

The autonomous community consists of a single province (region), unlike most autonomous communities, which have several provinces, within the same region. Because of this, the autonomous community and the region are operated as one unit of government. The city of Murcia is the capital of the community.

See also List of municipalities in Murcia.

The Region of Murcia is bordered by Andalucía (provinces of Almería and Granada); Castilla-La Mancha (the province of Albacete), which was historically connected to Murcia until 1833; Valencian Community (province of Alicante); and the Mediterranean Sea. The highest mountain is Revolcadores (2015 m).

The community measures 11,313 km² and has a population of 1.2 million, of whom one-third live in the capital.

The region is located in the eastern part of the Cordilleras Béticas mountains and it is influenced by their orthography. These mountain ranges are divided as well in the Prebética, Subbética and Penibética mountain ranges (from north to the south).

Traditionally it has been considered that the peak of Revolcadores, pertaining to the bulk of the same name, was the highest point in the Region of Murcia, with 2,027 meters of height; but in measurements of the most recent maps of the SNIG (National Service of Geographic Information of Spain), Revolcadores appears with a height of1,999 m, and there is a mountain slightly further north of a similar altitude which is more elevated Los Obispos (The Bishops), with an altitude of 2,015 m.

Approximately 27% of the Murcian territory can be described as mountainous, 38% as intramountainous depressions and running valleys, and the remaining 35% as flat lands and plateaux.